What is the primary focus of an 'n-of-1' trial?

The primary focus of an 'n-of-1' trial is an intensive study of a single individual's response to treatment. This type of trial is designed to evaluate the effects of a specific intervention on an individual, allowing for personalized assessment and decision-making in clinical care. By examining the unique response of a single participant, n-of-1 trials can provide valuable insights into the efficacy and tolerance of treatment tailored to that person, rather than relying on average effects seen in larger groups.

These trials are particularly useful for chronic conditions where responses to treatment can vary widely among individuals. They facilitate a more nuanced understanding of how specific therapies work for a particular individual, effectively bridging the gap between clinical research and personal medical practice. This individualized approach stands in contrast to broader studies that use group data to draw general conclusions about treatment effectiveness.